Monocyte/Macrophage Abnormalities Specific to Rheumatoid Arthritis Are Linked to miR-155 and Are Differentially Modulated by Different TNF Inhibitors

Proinflammatory macrophages and miR-155 are increased in patients with rheumatoid arthritis (RA). We studied membrane TNF (mTNF) expression on blood monocytes, polarization into macrophages, miR-155 expression, and the effect of anti-TNF on these biomarkers in RA patients. Sixty-seven RA patients an...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Paoletti, Audrey, Rohmer, Julien, Ly, Bineta, Pascaud, Juliette, Rivière, Elodie, Seror, Raphaele, Le Goff, Benoit, Nocturne, Gaetane, Mariette, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2019
Assuntos:
Autoimmunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755128/
https://ncbi.nlm.nih.gov/pubmed/31484730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900386
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