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Effects of angiotensin-II on brain endothelial cell permeability via PPARalpha regulation of para- and trans-cellular pathways

Angiotensin-II (Ang-II) is a key factor in hypertension, diabetes and aging, which are all primary risk factors for CNS disease. Furthermore, Ang-II may play under- appreciated roles in neurogenesis, angiogenesis and CNS remodeling. Therefore, any contemplated attempts for neurorestorative therapies...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Brain Res
Hauptverfasser: Guo, Shuzhen, Som, Angel T., Arai, Ken, Lo, Eng H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755037/
https://ncbi.nlm.nih.gov/pubmed/31356784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2019.146353
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