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Cell wall inhibition in L-forms or via β-lactam antibiotics induces reactive oxygen-mediated bacterial killing through increased glycolytic flux

The peptidoglycan (PG) cell wall is an essential structure for the growth of most bacteria. However, many are capable of switching into a wall-deficient L-form state, which is resistant to antibiotics that target cell wall synthesis, under osmoprotective conditions, including host environments. L-fo...

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Detalhes bibliográficos
Publicado no:Nat Microbiol
Main Authors: Kawai, Yoshikazu, Mercier, Romain, Mickiewicz, Katarzyna, Serafini, Agnese, de Carvalho, Luiz Pedro Sório, Errington, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755032/
https://ncbi.nlm.nih.gov/pubmed/31285586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-019-0497-3
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