Interleukin-1 causes CNS inflammatory cytokine expression via endothelia-microglia bi-cellular signaling

As a major producer of the inflammatory cytokine interleukin-1 (IL-1), peripheral macrophages can augment IL-1 expression via type 1 IL-1 receptor (IL-1R1) mediated autocrine self-amplification. In the CNS, microglial cells are the major producers of inflammatory cytokines, but express negligible le...

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Bibliografiska uppgifter
I publikationen:Brain Behav Immun
Huvudupphovsmän: Zhu, Ling, Liu, Xiaoyu, Nemeth, Daniel P., DiSabato, Damon J., Witcher, Kristina G., Mckim, Daniel B., Oliver, Braedan, Le, Xi, Gorantla, Gowthami, Berdysz, Olimpia, Li, Jiaoni, Ramani, Aishwarya D., Chen, Zhibiao, Wu, Dongcheng, Godbout, Jonathan P., Quan, Ning
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754782/
https://ncbi.nlm.nih.gov/pubmed/31228609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2019.06.026
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