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Encorafenib and binimetinib for the treatment of BRAF-mutated metastatic melanoma in the setting of combined hepatic and renal impairment

Inhibitors of BRAF, a gene coding a protein called B-raf, with or without inhibitors of MEK (MAPK/extracellular signal-regulated kinase) are often used as palliative treatment in BRAF-mutated metastatic melanoma. Recent data show improved progression-free survival with encorafenib with binimetinib,...

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Detalhes bibliográficos
Publicado no:BMJ Case Rep
Main Authors: Ngo, P, Bycroft, R
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754663/
https://ncbi.nlm.nih.gov/pubmed/31527213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bcr-2019-230974
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