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Many human RNA viruses show extraordinarily stringent selective constraints on protein evolution
How negative selection, positive selection, and population size contribute to the large variation in nucleotide substitution rates among RNA viruses remains unclear. Here, we studied the ratios of nonsynonymous-to-synonymous substitution rates (d(N)/d(S)) in protein-coding genes of human RNA and DNA...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6754614/ https://ncbi.nlm.nih.gov/pubmed/31484772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1907626116 |
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