Compound danshen dripping pills normalize a reprogrammed metabolism of myocardial ischemia rats to interpret its time-dependent efficacy in clinic trials: a metabolomic study

INTRODUCTION: Clinical trials of Compound danshen dripping pills (CDDP) indicated distinct improvement in patients with chronic stable angina. Daily fluctuation of therapeutic effect agreed with a peak-valley PK profile during a 4-week CDDP regimen, but stabilized after 8-week treatment. OBJECTIVES:...

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Dettagli Bibliografici
Pubblicato in:Metabolomics
Autori principali: Aa, Nan, Guo, Jia-Hua, Cao, Bei, Sun, Run-Bin, Ma, Xiao-Hui, Chu, Yang, Zhou, Shui-Ping, Aa, Ji-Ye, Yang, Zhi-Jian, Sun, He, Wang, Guang-Ji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754357/
https://ncbi.nlm.nih.gov/pubmed/31541307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-019-1577-3
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