Cell membrane-coated magnetic nanocubes with a homotypic targeting ability increase intracellular temperature due to ROS scavenging and act as a versatile theranostic system for glioblastoma multiforme

In this study, we synthesized hybrid nanocubes composed of magnetite (Fe(3)O(4)) and manganese dioxide (MnO(2)), coated with U-251 MG cell-derived membranes (CM-NCubes). The CM-NCubes demonstrated a concentration-dependent oxygen generation (up to 15%), and, for the first time in literature, we show...

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Detalhes bibliográficos
Publicado no:Adv Healthc Mater
Main Authors: Tapeinos, Christos, Tomatis, Francesca, Battaglini, Matteo, Larrañaga, Aitor, Marino, Attilio, Telleria, Iker Aguirrezabal, Angelakeris, Makis, Debellis, Doriana, Drago, Filippo, Brero, Francesca, Arosio, Paolo, Lascialfari, Alessandro, Petretto, Andrea, Sinibaldi, Edoardo, Ciofani, Gianni
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754263/
https://ncbi.nlm.nih.gov/pubmed/31389193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201900612
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