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Mice deficient in NKLAM have attenuated inflammatory cytokine production in a Sendai virus pneumonia model

Recent studies have begun to elucidate a role for E3 ubiquitin ligases as important mediators of the innate immune response. Our previous work defined a role for the ubiquitin ligase natural killer lytic-associated molecule (NKLAM/RNF19b) in mouse and human innate immunity. Here, we present novel da...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lawrence, Donald W., Shornick, Laurie P., Kornbluth, Jacki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754162/
https://ncbi.nlm.nih.gov/pubmed/31539400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222802
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