Elucidating the putative link between prefrontal neurotransmission, functional connectivity, and affective symptoms in irritable bowel syndrome

Altered neural mechanisms are well-acknowledged in irritable bowel syndrome (IBS), a disorder of brain-gut-communication highly comorbid with anxiety and depression. As a key hub in corticolimbic inhibition, medial prefrontal cortex (mPFC) may be involved in disturbed emotion regulation in IBS. Howe...

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Foilsithe in:Sci Rep
Main Authors: Icenhour, Adriane, Tapper, Sofie, Bednarska, Olga, Witt, Suzanne T., Tisell, Anders, Lundberg, Peter, Elsenbruch, Sigrid, Walter, Susanna
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753205/
https://ncbi.nlm.nih.gov/pubmed/31537890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50024-3
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