Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease

Identifying methylation quantitative trait loci (meQTLs) and integrating them with disease-associated variants from genome-wide association studies (GWAS) may illuminate functional mechanisms underlying genetic variant-disease associations. Here, we perform GWAS of >415 thousand CpG methylation s...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Huan, Tianxiao, Joehanes, Roby, Song, Ci, Peng, Fen, Guo, Yichen, Mendelson, Michael, Yao, Chen, Liu, Chunyu, Ma, Jiantao, Richard, Melissa, Agha, Golareh, Guan, Weihua, Almli, Lynn M., Conneely, Karen N., Keefe, Joshua, Hwang, Shih-Jen, Johnson, Andrew D., Fornage, Myriam, Liang, Liming, Levy, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753136/
https://ncbi.nlm.nih.gov/pubmed/31537805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12228-z
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