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Novel breast cancer screening: combined expression of miR-21 and MMP-1 in urinary exosomes detects 95% of breast cancer without metastasis

Serum and tissue miR-21 expression in patients with breast cancer (BC) is a useful biomarker for cancer diagnosis, progression, and treatment. Matrix metalloproteinase-1 (MMP-1) is also important in breast cancer carcinogenesis. However, miR-21 and MMP-1/CD63 in urine exosomes in these patients have...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ando, Wataru, Kikuchi, Kiyoshi, Uematsu, Takayuki, Yokomori, Hiroaki, Takaki, Takashi, Sogabe, Masaya, Kohgo, Yutaka, Otori, Katsuya, Ishikawa, Shigemi, Okazaki, Isao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753125/
https://ncbi.nlm.nih.gov/pubmed/31537868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50084-5
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