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Osmolytes ameliorate the effects of stress in the absence of the heat shock protein Hsp104 in Saccharomyces cerevisiae

Aggregation of the prion protein has strong implications in the human prion disease. Sup35p is a yeast prion, and has been used as a model protein to study the disease mechanism. We have studied the pattern of Sup35p aggregation inside live yeast cells under stress, by using confocal microscopy, flu...

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Publicado en:PLoS One
Main Authors: Bandyopadhyay, Arnab, Bose, Indrani, Chattopadhyay, Krishnananda
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6752772/
https://ncbi.nlm.nih.gov/pubmed/31536559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222723
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