In vivo antibacterial efficacy of nitric oxide-releasing hyperbranched polymers against Porphyromonas gingivalis

The in vivo antibacterial activity of NO-releasing hyperbranched polymers was evaluated against Porphyromonas gingivalis, a key oral pathogen associated with periodontitis, using a murine subcutaneous chamber model. Escalating doses of NO-releasing polymers (1.5, 7.5, and 37.5 mg/kg) were administer...

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Udgivet i:Mol Pharm
Main Authors: Yang, Lei, Jing, Li, Jiao, Yizu, Lu, Fei, Marchesan, Julie T., Offenbacher, Steven, Schoenfisch, Mark H.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6752707/
https://ncbi.nlm.nih.gov/pubmed/31361146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.9b00671
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