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Integrative genomic analyses of APOBEC-mutational signature, expression and germline deletion of APOBEC3 genes, and immunogenicity in multiple cancer types
BACKGROUND: Although APOBEC-mutational signature is found in tumor tissues of multiple cancers, how a common germline APOBEC3A/B deletion affects the mutational signature remains unclear. METHODS: Using data from 10 cancer types generated as part of TCGA, we performed integrative genomic and associa...
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| Publicat a: | BMC Med Genomics |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6751822/ https://ncbi.nlm.nih.gov/pubmed/31533728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0579-3 |
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