Optimization of nanoemulsion containing gemcitabine and evaluation of its cytotoxicity towards human fetal lung fibroblast (MRC5) and human lung carcinoma (A549) cells

BACKGROUND: Gemcitabine (GEM) is a chemotherapeutic agent, which is known to battle cancer but challenging due to its hydrophilic nature. Nanoemulsion is water-in-oil (W/O) nanoemulsion shows potential as a carrier system in delivering gemcitabine to the cancer cell. METHODS: The behaviour of GEM in...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Wahgiman, Nadiatul Atiqah, Salim, Norazlinaliza, Abdul Rahman, Mohd Basyaruddin, Ashari, Siti Efliza
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751780/
https://ncbi.nlm.nih.gov/pubmed/31686809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S212635
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