The Oxysterol Synthesising Enzyme CH25H Contributes to the Development of Intestinal Fibrosis

Intestinal fibrosis and stenosis are common complications of Crohn’s disease [CD], frequently requiring surgery. Anti-inflammatory strategies can only partially prevent fibrosis; hence, anti-fibrotic therapies remain an unmet clinical need. Oxysterols are oxidised cholesterol derivatives with import...

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Dettagli Bibliografici
Pubblicato in:J Crohns Colitis
Autori principali: Raselli, T, Wyss, A, Gonzalez Alvarado, M N, Weder, B, Mamie, C, Spalinger, M R, Van Haaften, W T, Dijkstra, G, Sailer, A W, Imenez Silva, P H, Wagner, C A, Tosevski, V, Leibl, Sebastian, Scharl, M, Rogler, G, Hausmann, M, Misselwitz, B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751338/
https://ncbi.nlm.nih.gov/pubmed/31220227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjz039
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