Rescue of Noradrenergic System as a Novel Pharmacological Strategy in the Treatment of Chronic Pain: Focus on Microglia Activation

Different types of pain can evolve toward a chronic condition characterized by hyperalgesia and allodynia, with an abnormal response to normal or even innocuous stimuli, respectively. A key role in endogenous analgesia is recognized to descending noradrenergic pathways that originate from the locus...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Caraci, Filippo, Merlo, Sara, Drago, Filippo, Caruso, Giuseppe, Parenti, Carmela, Sortino, Maria Angela
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751320/
https://ncbi.nlm.nih.gov/pubmed/31572196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01024
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