Lung endothelial cell antigen cross-presentation to CD8(+)T cells drives malaria-associated lung injury

Malaria-associated acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) are life-threatening manifestations of severe malaria infections. The pathogenic mechanisms that lead to respiratory complications, such as vascular leakage, remain unclear. Here, we confirm that depleting CD8(...

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Vydáno v:Nat Commun
Hlavní autoři: Claser, Carla, Nguee, Samantha Yee Teng, Balachander, Akhila, Wu Howland, Shanshan, Becht, Etienne, Gunasegaran, Bavani, Hartimath, Siddesh V., Lee, Audrey W. Q., Theng Theng Ho, Jacqueline, Bing Ong, Chee, Newell, Evan W., Goggi, Julian, Guan Ng, Lai, Renia, Laurent
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751193/
https://ncbi.nlm.nih.gov/pubmed/31534124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12017-8
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