Lung endothelial cell antigen cross-presentation to CD8(+)T cells drives malaria-associated lung injury

Malaria-associated acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) are life-threatening manifestations of severe malaria infections. The pathogenic mechanisms that lead to respiratory complications, such as vascular leakage, remain unclear. Here, we confirm that depleting CD8(...

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Publicado no:Nat Commun
Main Authors: Claser, Carla, Nguee, Samantha Yee Teng, Balachander, Akhila, Wu Howland, Shanshan, Becht, Etienne, Gunasegaran, Bavani, Hartimath, Siddesh V., Lee, Audrey W. Q., Theng Theng Ho, Jacqueline, Bing Ong, Chee, Newell, Evan W., Goggi, Julian, Guan Ng, Lai, Renia, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751193/
https://ncbi.nlm.nih.gov/pubmed/31534124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12017-8
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