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The Dual Roles of the Atypical Protein Kinase Cs in Cancer

Atypical Protein Kinase C (aPKC) isozymes, PKCλ/ι and PKCζ, are now considered fundamental regulators of tumorigenesis. However, the specific separation of functions that determine their different roles in cancer is still being unraveled. Both aPKCs have pleiotropic context-dependent functions that...

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Dettagli Bibliografici
Pubblicato in:Cancer Cell
Autori principali: Reina-Campos, Miguel, Diaz-Meco, Maria T., Moscat, Jorge
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751000/
https://ncbi.nlm.nih.gov/pubmed/31474570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2019.07.010
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