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The Dual Roles of the Atypical Protein Kinase Cs in Cancer

Atypical Protein Kinase C (aPKC) isozymes, PKCλ/ι and PKCζ, are now considered fundamental regulators of tumorigenesis. However, the specific separation of functions that determine their different roles in cancer is still being unraveled. Both aPKCs have pleiotropic context-dependent functions that...

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Bibliographic Details
Published in:Cancer Cell
Main Authors: Reina-Campos, Miguel, Diaz-Meco, Maria T., Moscat, Jorge
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751000/
https://ncbi.nlm.nih.gov/pubmed/31474570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2019.07.010
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