Large-scale RNAi screen identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis

Mitochondria are highly dynamic organelles. Through a large-scale in vivo RNA interference (RNAi) screen that covered around a quarter of the Drosophila melanogaster genes (4000 genes), we identified 578 genes whose knockdown led to aberrant shapes or distributions of mitochondria. The complex analy...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Zhou, Jia, Xu, Lingna, Duan, Xiuying, Liu, Wei, Zhao, Xiaocui, Wang, Xi, Shang, Weina, Fang, Xuefei, Yang, Huan, Jia, Lijun, Bai, Jian, Zhao, Jiayao, Wang, Liquan, Tong, Chao
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6750926/
https://ncbi.nlm.nih.gov/pubmed/31555733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax0365
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