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PLK1 contributes to autophagy by regulating MYC stabilization in osteosarcoma cells

BACKGROUND: PLK1, a typical PLK protein, is the main driver of cancer cell growth and proliferation. It is an inhibitor of the protein kinases that is currently being investigated in clinical studies. It is often used as a tumor marker, as high PLK1 expression correlates with poor prognosis in cance...

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Detalles Bibliográficos
Publicado en:Onco Targets Ther
Main Authors: Mo, Hao, He, Juliang, Yuan, Zhenchao, Wu, Zhenjie, Liu, Bin, Lin, Xiang, Guan, Jian
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6750617/
https://ncbi.nlm.nih.gov/pubmed/31571905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S210575
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