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Inverted translational control of eukaryotic gene expression by ribosome collisions
The canonical model of eukaryotic translation posits that efficient translation initiation increases protein expression and mRNA stability. Contrary to this model, we find that increasing initiation rate can decrease both protein expression and stability of certain mRNAs in the budding yeast Sacchar...
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| Publicado no: | PLoS Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6750593/ https://ncbi.nlm.nih.gov/pubmed/31532761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000396 |
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