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Inverted translational control of eukaryotic gene expression by ribosome collisions

The canonical model of eukaryotic translation posits that efficient translation initiation increases protein expression and mRNA stability. Contrary to this model, we find that increasing initiation rate can decrease both protein expression and stability of certain mRNAs in the budding yeast Sacchar...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Biol
Prif Awduron: Park, Heungwon, Subramaniam, Arvind R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6750593/
https://ncbi.nlm.nih.gov/pubmed/31532761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000396
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