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C57BL/6 and 129 inbred mouse strains differ in Gbp2 and Gbp2b expression in response to inflammatory stimuli in vivo

Background: Infections cause the production of inflammatory cytokines such as Interferon gamma (IFNγ). IFNγ in turn prompts the upregulation of a range of host defence proteins including members of the family of guanylate binding proteins (Gbps). In humans and mice alike, GBPs restrict the intracell...

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Detalhes bibliográficos
Publicado no:Wellcome Open Res
Main Authors: Clough, Barbara, Finethy, Ryan, Khan, Rabia T., Fisch, Daniel, Jordan, Sarah, Patel, Harshil, Coers, Jörn, Frickel, Eva-Maria
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Limited 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6749937/
https://ncbi.nlm.nih.gov/pubmed/31544161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.15329.1
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