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Reproductive characteristics are associated with gene-specific promoter methylation status in breast cancer

BACKGROUND: Reproductive characteristics are well-established risk factors for breast cancer, but the underlying mechanisms are not fully resolved. We hypothesized that altered DNA methylation, measured in tumor tissue, could act in concert with reproductive factors to impact breast carcinogenesis....

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: McCullough, Lauren E., Collin, Lindsay J., Conway, Kathleen, White, Alexandra J., Cho, Yoon Hee, Shantakumar, Sumitra, Terry, Mary Beth, Teitelbaum, Susan L., Neugut, Alfred I., Santella, Regina M., Chen, Jia, Gammon, Marilie D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6749688/
https://ncbi.nlm.nih.gov/pubmed/31533668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6120-4
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