Detrimental Effect of Type I IFNs During Acute Lung Infection With Pseudomonas aeruginosa Is Mediated Through the Stimulation of Neutrophil NETosis

Pseudomonas aeruginosa is an opportunistic multidrug-resistant pathogen, able to grow in biofilms. It causes life-threatening complications in diseases characterized by the up-regulation of type I interferon (IFN) signaling, such as cancer or viral infections. Since type I IFNs regulate multiple fun...

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Foilsithe in:Front Immunol
Main Authors: Pylaeva, Ekaterina, Bordbari, Sharareh, Spyra, Ilona, Decker, Anna Sophie, Häussler, Susanne, Vybornov, Vadim, Lang, Stephan, Jablonska, Jadwiga
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2019
Ábhair:
Immunology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6749149/
https://ncbi.nlm.nih.gov/pubmed/31572395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02190
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