Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer’s disease

Studies of rodent models of Alzheimer’s disease (AD) and of human tissues suggest that the retinal changes that occur in AD, including the accumulation of amyloid beta (Aβ), may serve as surrogate markers of brain Aβ levels. As Aβ has a wavelength-dependent effect on light scatter, we investigate th...

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Publicado no:Nat Commun
Main Authors: Hadoux, Xavier, Hui, Flora, Lim, Jeremiah K. H., Masters, Colin L., Pébay, Alice, Chevalier, Sophie, Ha, Jason, Loi, Samantha, Fowler, Christopher J., Rowe, Christopher, Villemagne, Victor L., Taylor, Edward N., Fluke, Christopher, Soucy, Jean-Paul, Lesage, Frédéric, Sylvestre, Jean-Philippe, Rosa-Neto, Pedro, Mathotaarachchi, Sulantha, Gauthier, Serge, Nasreddine, Ziad S., Arbour, Jean Daniel, Rhéaume, Marc-André, Beaulieu, Sylvain, Dirani, Mohamed, Nguyen, Christine T. O., Bui, Bang V., Williamson, Robert, Crowston, Jonathan G., van Wijngaarden, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748929/
https://ncbi.nlm.nih.gov/pubmed/31530809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12242-1
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