Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity

White adipose tissue (WAT) inflammation contributes to the development of insulin resistance in obesity. While the role of adipose tissue macrophage (ATM) pro-inflammatory signalling in the development of insulin resistance has been established, it is less clear how WAT inflammation is initiated. He...

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Dettagli Bibliografici
Pubblicato in:eLife
Autori principali: Petkevicius, Kasparas, Virtue, Sam, Bidault, Guillaume, Jenkins, Benjamin, Çubuk, Cankut, Morgantini, Cecilia, Aouadi, Myriam, Dopazo, Joaquin, Serlie, Mireille J, Koulman, Albert, Vidal-Puig, Antonio
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2019
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748830/
https://ncbi.nlm.nih.gov/pubmed/31418690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47990
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