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DeepAffinity: interpretable deep learning of compound–protein affinity through unified recurrent and convolutional neural networks

MOTIVATION: Drug discovery demands rapid quantification of compound–protein interaction (CPI). However, there is a lack of methods that can predict compound–protein affinity from sequences alone with high applicability, accuracy and interpretability. RESULTS: We present a seamless integration of dom...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Karimi, Mostafa, Wu, Di, Wang, Zhangyang, Shen, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748780/
https://ncbi.nlm.nih.gov/pubmed/30768156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz111
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