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Renal mitochondrial oxidative stress is enhanced by the reduction of Sirt3 activity, in Zucker diabetic fatty rats

Objectives: Mitochondrial oxidative stress is involved in the pathogenesis of diabetic kidney disease. The objective of our study is to identify the mechanisms of renal mitochondrial oxidative stress, focusing on Sirt3, which is nicotinamide adenine dinucleotide (NAD(+); oxidized NAD)-dependent deac...

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Detalhes bibliográficos
Publicado no:Redox Rep
Main Authors: Ogura, Yoshio, Kitada, Munehiro, Monno, Itaru, Kanasaki, Keizo, Watanabe, Ai, Koya, Daisuke
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748695/
https://ncbi.nlm.nih.gov/pubmed/29897845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13510002.2018.1487174
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