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Renal mitochondrial oxidative stress is enhanced by the reduction of Sirt3 activity, in Zucker diabetic fatty rats

Objectives: Mitochondrial oxidative stress is involved in the pathogenesis of diabetic kidney disease. The objective of our study is to identify the mechanisms of renal mitochondrial oxidative stress, focusing on Sirt3, which is nicotinamide adenine dinucleotide (NAD(+); oxidized NAD)-dependent deac...

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Dades bibliogràfiques
Publicat a:Redox Rep
Autors principals: Ogura, Yoshio, Kitada, Munehiro, Monno, Itaru, Kanasaki, Keizo, Watanabe, Ai, Koya, Daisuke
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748695/
https://ncbi.nlm.nih.gov/pubmed/29897845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13510002.2018.1487174
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