Looking for therapeutic antibodies in next-generation sequencing repositories

Recently it has become possible to query the great diversity of natural antibody repertoires using next-generation sequencing (NGS). These methods are capable of producing millions of sequences in a single experiment. Here we compare clinical-stage therapeutic antibodies to the ~1b sequences from 60...

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Bibliografiske detaljer
Udgivet i:MAbs
Main Authors: Krawczyk, Konrad, Raybould, Matthew I. J., Kovaltsuk, Aleksandr, Deane, Charlotte M.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Brief Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748601/
https://ncbi.nlm.nih.gov/pubmed/31216939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1633884
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