The polyether ionophore salinomycin targets multiple cellular pathways to block proliferative vitreoretinopathy pathology

Proliferative vitreoretinopathy (PVR) is characterized by membranes that form in the vitreous cavity and on both surfaces of the retina, which results in the formation of tractional membranes that can cause retinal detachment and intrinsic fibrosis of the retina, leading to retina foreshortening. Cu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Heffer, Alison M., Proaño, Jacob, Roztocil, Elisa, Phipps, Richard P., Feldon, Steven E., Huxlin, Krystel R., Sime, Patricia J., Libby, Richard T., Woeller, Collynn F., Kuriyan, Ajay E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748436/
https://ncbi.nlm.nih.gov/pubmed/31527897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222596
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