Oncogenic Ect2 signaling regulates rRNA synthesis in NSCLC

The Rho GTPase family members Rac1, Cdc42 and RhoA play key contributory roles in the transformed phenotype of human cancers. Epithelial Cell Transforming Sequence 2 (Ect2), a guanine nucleotide exchange factor (GEF) for these Rho GTPases, has also been implicated in a variety of human cancers. We h...

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Detalhes bibliográficos
Publicado no:Small GTPases
Main Authors: Justilien, Verline, Lewis, Kayla C., Murray, Nicole R., Fields, Alan P.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Brief Report - Commissioned
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748369/
https://ncbi.nlm.nih.gov/pubmed/28657426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1335274
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