Multipoint targeting of TGF-β/Wnt transactivation circuit with microRNA 384-5p for cardiac fibrosis

Cardiac fibrosis is a common precursor to ventricular dysfunction and eventual heart failure, and cardiac fibrosis begins with cardiac fibroblast activation. Here we have demonstrated that the TGF-β signaling pathway and Wnt signaling pathway formed a transactivation circuit during cardiac fibroblas...

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Pubblicato in:Cell Death Differ
Autori principali: Seo, Hyang-Hee, Lee, Seahyoung, Lee, Chang Youn, Lee, Jiyun, Shin, Sunhye, Song, Byeong-Wook, Kim, Il-Kwon, Choi, Jung-Won, Lim, Soyeon, Kim, Sang Woo, Hwang, Ki-Chul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748152/
https://ncbi.nlm.nih.gov/pubmed/30206318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0187-3
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