Inhibition of EZH2 induces NK cell-mediated differentiation and death in muscle-invasive bladder cancer

Lysine-specific demethylase 6A (KDM6A) and members of the Switch/Sucrose Non-Fermentable (SWI/SNF) family are known to counteract the activity of Enhancer of Zeste Homolog 2 (EZH2), which is often overexpressed and is associated with poor prognosis in muscle-invasive bladder cancer. Here we provide...

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Udgivet i:Cell Death Differ
Main Authors: Ramakrishnan, Swathi, Granger, Victoria, Rak, Monika, Hu, Qiang, Attwood, Kristopher, Aquila, Lanni, Krishnan, Nithya, Osiecki, Rafal, Azabdaftari, Gissou, Guru, Khurshid, Chatta, Gurkamal, Gueron, Geraldine, McNally, Lacey, Ohm, Joyce, Wang, Jianmin, Woloszynska, Anna
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748105/
https://ncbi.nlm.nih.gov/pubmed/30692641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0278-9
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