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PDMS-PMOXA-Nanoparticles Featuring a Cathepsin B-Triggered Release Mechanism

Background: It was our intention to develop cathepsin B-sensitive nanoparticles for tumor-site-directed release. These nanoparticles should be able to release their payload as close to the tumor site with a decrease of off-target effects in mind. Cathepsin B, a lysosomal cysteine protease, is associ...

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Podrobná bibliografie
Vydáno v:Materials (Basel)
Hlavní autoři: Ehrsam, Daniel, Porta, Fabiola, Hussner, Janine, Seibert, Isabell, Meyer zu Schwabedissen, Henriette E
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747961/
https://ncbi.nlm.nih.gov/pubmed/31484396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ma12172836
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