Sirtuin Inhibitors Are Broadly Antiviral against Arboviruses

Arthropod-borne viruses are diverse pathogens and are often associated with human disease. These viruses span multiple genera, including flaviviruses, alphaviruses, and bunyaviruses. In a high-throughput drug screen, we found that tenovin-1 was antiviral against the flaviviruses Zika virus and dengu...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Hackett, Brent A., Dittmar, Mark, Segrist, Elisha, Pittenger, Nathan, To, Julie, Griesman, Trevor, Gordesky-Gold, Beth, Schultz, David C., Cherry, Sara
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747726/
https://ncbi.nlm.nih.gov/pubmed/31289184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01446-19
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