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Different Dynamics in 6aJL2 Proteins Associated with AL Amyloidosis, a Conformational Disease

Light-chain amyloidosis (AL) is the most common systemic amyloidosis and is caused by the deposition of mainly insoluble immunoglobulin light chain amyloid fibrils in multiple organs, causing organ failure and eventually death. The germ-line λ6a has been implicated in AL, where a single point mutant...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Maya-Martinez, Roberto, French-Pacheco, Leidys, Valdés-García, Gilberto, Pastor, Nina, Amero, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747610/
https://ncbi.nlm.nih.gov/pubmed/31438515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20174078
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