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Pachypodol, a Methoxyflavonoid Isolated from Pogostemon cablin Bentham Exerts Antioxidant and Cytoprotective Effects in HepG2 Cells: Possible Role of ERK-Dependent Nrf2 Activation

Oxidative stress has been implicated in the pathogenesis of many diseases including chronic liver diseases. Nrf2 is a master transcriptional factor regulating the induction of cellular antioxidant defense systems. Here, the Nrf2-activating effect of the crude methanol extract of dried leaves of Pogo...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kim, Eun Kyung, Kim, Ji Hoon, Jeong, Soyeon, Choi, Yong Won, Choi, Hyun Jung, Kim, Chul Young, Kim, Young-Mi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747508/
https://ncbi.nlm.nih.gov/pubmed/31438541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20174082
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