Effects of Grape Seed Extract and Proanthocyanidin B2 on In Vitro Proliferation, Viability, Steroidogenesis, Oxidative Stress, and Cell Signaling in Human Granulosa Cells

Reactive oxygen species (ROS) which lead to oxidative stress affect ovarian function. Grape seed extract (GSE) could be proposed as an effective antioxidant, particularly due to its proanthocyanidin content. In this study, we investigated a dose effect (0, 0.01, 0.1, 1, 10, 50, and 100 μg/mL) of GSE...

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Publicat a:Int J Mol Sci
Autors principals: Barbe, Alix, Ramé, Christelle, Mellouk, Namya, Estienne, Anthony, Bongrani, Alice, Brossaud, Adeline, Riva, Antonella, Guérif, Fabrice, Froment, Pascal, Dupont, Joëlle
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747392/
https://ncbi.nlm.nih.gov/pubmed/31466336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20174215
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