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Mutual Enhancement of Opioid and Adrenergic Receptors by Combinations of Opioids and Adrenergic Ligands Is Reflected in Molecular Complementarity of Ligands: Drug Development Possibilities

Crosstalk between opioid and adrenergic receptors is well characterized and due to interactions between second messenger systems, formation of receptor heterodimers, and extracellular allosteric binding regions. Both classes of receptors bind both sets of ligands. We propose here that receptor cross...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Root-Bernstein, Robert, Churchill, Beth, Turke, Miah, Tiruttani Subhramanyam, Udaya K., Labahn, Joerg
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747318/
https://ncbi.nlm.nih.gov/pubmed/31450631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20174137
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