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Cytosolic Copper Binding by a Bacterial Storage Protein and Interplay with Copper Efflux

Escherichia coli has a well-characterized copper (Cu) transporting ATPase (CopA) that removes this potentially toxic metal ion from the cytosol. Growth of the strain lacking CopA (ΔcopA) is inhibited above 0.5 mM Cu, whilst a similar effect does not occur in wild type (WT) E. coli until over 2.5 mM...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Lee, Jaeick, Dennison, Christopher
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747150/
https://ncbi.nlm.nih.gov/pubmed/31450649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20174144
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