Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma

Natural killer/T cell lymphoma (NKTCL) is a rare and aggressive malignancy with a higher prevalence in Asia and South America. However, the molecular genetic mechanisms underlying NKTCL remain unclear. Here, we identify somatic mutations of GNAQ (encoding the T96S alteration of Gαq protein) in 8.7%...

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Publicado no:Nat Commun
Main Authors: Li, Zhaoming, Zhang, Xudong, Xue, Weili, Zhang, Yanjie, Li, Chaoping, Song, Yue, Mei, Mei, Lu, Lisha, Wang, Yingjun, Zhou, Zhiyuan, Jin, Mengyuan, Bian, Yangyang, Zhang, Lei, Wang, Xinhua, Li, Ling, Li, Xin, Fu, Xiaorui, Sun, Zhenchang, Wu, Jingjing, Nan, Feifei, Chang, Yu, Yan, Jiaqin, Yu, Hui, Feng, Xiaoyan, Wang, Guannan, Zhang, Dandan, Fu, Xuefei, Zhang, Yuan, Young, Ken H., Li, Wencai, Zhang, Mingzhi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746819/
https://ncbi.nlm.nih.gov/pubmed/31527657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12032-9
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