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Are there different evidence thresholds for genomic vs. clinical precision medicine? A VOI-based framework applied to antiplatelet drug therapy

OBJECTIVE: To evaluate evidence thresholds for clinically-guided precision medicine (PM) vs. genomically-guided PM. METHODS: We develop an “evidence threshold criterion” (ETC) that is the time-weighted difference between expected value of perfect information (EVPI) and incremental net health benefit...

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Vydáno v:Value Health
Hlavní autoři: Guzauskas, Gregory F., Basu, Anirban, Serbin, Michael, Carlson, Josh J., Veenstra, David L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746330/
https://ncbi.nlm.nih.gov/pubmed/31511188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jval.2019.03.023
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