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Reagent Controlled Direct Dehydrative Glycosylation with 2-Deoxy Sugars: Construction of the Saquayamycin Z Pentasaccharide

The first synthesis of the pentasaccharide fragment of the angucycline antibiotic saquayamycin Z is described. By using our sulfonyl chloride mediated reagent controlled dehydrative glycosylation, we are able to assemble the glycosidic linkages with high levels of anomeric selectivity. The total syn...

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Publicat a:Org Lett
Autors principals: Mizia, J. Colin, Bennett, Clay S.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746326/
https://ncbi.nlm.nih.gov/pubmed/31305082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b02056
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