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A novel group of spindle cell tumors defined by S100 and CD34 co-expression shows recurrent fusions involving RAF1, BRAF, and NTRK1/2 genes

Tumors characterized by co-expression of S100 and CD34, in the absence of SOX10, remain difficult to classify. Triggered by a few index cases with monomorphic cytomorphology and distinctive stromal and perivascular hyalinization, immunopositivity for S100 and CD34, and RAF1 and NTRK1 fusions, the au...

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Detalhes bibliográficos
Publicado no:Genes Chromosomes Cancer
Main Authors: Suurmeijer, Albert J. H., Dickson, Brendan C., Swanson, David, Zhang, Lei, Sung, Yun-Shao, Cotzia, Paolo, Fletcher, Christopher D. M., Antonescu, Cristina R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746236/
https://ncbi.nlm.nih.gov/pubmed/30276917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22671
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