Estrogen metabolism in menopausal hormone users in the Women’s Health Initiative Observational Study: Does it differ between estrogen plus progestin and estrogen alone?

The WHI found an unexpected reduced breast cancer risk in women using CEE alone. We hypothesized CEE alone induces estrogen hydroxylation along the 2-pathway rather than the competing 16-pathway, a pattern linked to reduced postmenopausal breast cancer risk. 1864 women in a WHIOS case-control study...

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Udgivet i:Int J Cancer
Main Authors: Falk, Roni T., Manson, JoAnn E., Barnabei, Vanessa M., Anderson, Garnet L., Brinton, Louise A., Rohan, Thomas E., Cauley, Jane A., Chen, Chu, Coburn, Sally B., Pfeiffer, Ruth M., Reding, Kerryn W., Sarto, Gloria E., Wentzensen, Nicolas, Chlebowski, Rowan T., Xu, Xia, Trabert, Britton
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746113/
https://ncbi.nlm.nih.gov/pubmed/30183089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31851
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