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Development of Fluorogenic Substrates of α-l-Fucosidase Useful for Inhibitor Screening and Gene-expression Profiling

[Image: see text] Inhibitors of human α-l-fucosidases, tissue α-l-fucosidase (tFuc), and plasma α-l-fucosidase reportedly play roles in multiple diseases, suggesting their therapeutic potential for gastric disease associated with Helicobacter pylori and fucosidosis. Terminal fucose linkages on glyco...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Miura, Kazuki, Tsukagoshi, Takumi, Hirano, Takako, Nishio, Toshiyuki, Hakamata, Wataru
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746076/
https://ncbi.nlm.nih.gov/pubmed/31531202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00259
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