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The Impact of the Cellular Origin in Acute Myeloid Leukemia: Learning From Mouse Models

Acute myeloid leukemia (AML) is a genetically heterogeneous disease driven by a limited number of cooperating mutations. There is a long-standing debate as to whether AML driver mutations occur in hematopoietic stem or in more committed progenitor cells. Here, we review how different mouse models, d...

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Detalhes bibliográficos
Publicado no:Hemasphere
Main Authors: Fisher, James Neil, Kalleda, Natarajaswamy, Stavropoulou, Vaia, Schwaller, Juerg
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745939/
https://ncbi.nlm.nih.gov/pubmed/31723801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HS9.0000000000000152
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