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Molecular characterization of AML with RUNX1-RUNX1T1 at diagnosis and relapse reveals net loss of co-mutations

AML with RUNX1-RUNX1T1 fusion is a WHO entity with a favorable outcome following intensive chemotherapy. The absence of RUNX1-RUNX1T1 transcripts in remission defines complete molecular response and correlates with a superior survival. However, a significant proportion of patients still relapses and...

詳細記述

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書誌詳細
出版年:Hemasphere
主要な著者: Höllein, Alexander, Nadarajah, Niroshan, Meggendorfer, Manja, Jeromin, Sabine, Kern, Wolfgang, Haferlach, Claudia, Haferlach, Torsten
フォーマット: Artigo
言語:Inglês
出版事項: Wolters Kluwer Health 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745937/
https://ncbi.nlm.nih.gov/pubmed/31723813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HS9.0000000000000178
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